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Diabetic retinopathy


Who gets diabetic retinopathy?


Page 3 of 9:
Summary
What is diabetic retinopathy?
Who gets diabetic retinopathy?
Influencing factors?
Eye examination frequency?
How is diabetic retinopathy detected?
What are the signs to look out for?
What treatment is available?
Contraindications to treatment
References



Diabetic retinopathy is the most common ophthalmic complication of diabetes. Although the exact mechanisms by which hyperglycaemia causes any complication of diabetes are not completely known, the relationship between poor glycaemic control and the development of diabetic retinopathy has been clearly shown. [Stratton et al, 2000; The DCCT Research Group, 1993]

As with all complications of diabetes, the duration of diabetes is a major risk factor associated with its development (Figures 1 and 2).

Within 5 years of diagnosis of diabetes:

  • About 25% of people with Type 1 diabetes have retinopathy.

  • 40% of people with Type 2 diabetes who are taking insulin (ie have more advanced disease) have retinopathy.

  • 24% of people with Type 2 diabetes who are not taking insulin will develop retinopathy.

Figure 1.
Prevalence of diabetic retinopathy in people with Type 1 diabetes.
[Klein et al, 1984]

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By the time of diagnosis, more than 20% of people with Type 2 diabetes may already have retinopathy [Aldingham et al, 1987; Harris et al, 1992; Harris et al, 1993]. Detectable retinopathy is likely to be present 4 to 7 years before diagnosis of diabetes [Harris et al, 1992].

Figure 2.
Prevalence of diabetic retinopathy in people with Type 2 diabetes.
[Klein et al, 1984]

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